I'm a little different than most for this, because I take amino acids as I'm missing my colon and have an ileostomy bag. My food goes through fast and I was starting to have things that were pointing to a nutritional deficiency, along with flat out already being in pretty poor health for a bunch of reasons. Anyway, we decided to give amino acids a try, seeing that if I couldn't break down the protein I ate in time, maybe I wasn't getting my essential amino acids.First, this stuff is rancid gross tasting. Totally vile. Like licking pennies dipped in dust and sprinkled with bleach. My routine is a heaping tablespoon into about 8oz of juice like a string cherry/cranberry/grape juice and then adding a good heart squeeze of Mio drops or the like. It still will taste soured and sorta gross, but it's no longer undrinkable.For me, the results are so worth it. I stopped losing mass from my legs, the daily headaches stopped, I no longer was constantly freezing. My blood work started to improve, and I started having more and more energy to function. I started feeling good, enough to actually start doing more activity. My doctor and I are very, very pleased.This particular brand is the highest listed dose of any amino acid supplement with no "extras" that I can find. Most don't label the amounts, or they add caffiene. I've run out before for a week, and the cruddy feelings - cold, tired and headachy) started coming back. I felt better within a couple days after starting back on it. I fo through about 1 bottle per month.I really think that folks with altered guts should talk with their doctor about trying this, especially if they have constant tiredness, chills and headaches. My doctor and I are very pleased with the results I've had.